A provocative new study reveals the complex effects of the space environment on human health, providing insight into potential damage to blood, cell structure and the immune system. The study focused on SpaceX's Inspiration4 mission, which successfully sent two men and two women into space in 2021 to orbit the Earth for three days and shed some light on the effects of space travel on the human body. The research data, derived directly from the Inspiration4 mission, shows that even a brief trip to space can significantly damage the human immune system, trigger an inflammatory response, and profoundly affect cell structure. In particular, space travel triggered unprecedented changes in cytokines that play a key role in immune response and muscle regulation but are not usually directly associated with inflammation. In particular, the study found a significant increase in muscle factors, which are physiological responses specific to skeletal muscle cells in microgravity, rather than a simple immune response. Although non-muscular tissues did not show changes in proteins associated with inflammation, specific leg muscles such as soleus and tibialis anterior muscles showed significant signs of metabolic activity, especially increased interleukin in the latter, further enhancing the activation of immune cells.

Koenigsegg Agera RS Chimera combines technologies from Agera RS, CC850, and Jesko. An Agera RS platform features the engine from the Jesko and the simulated manual gearbox from the CC850. Development took three years, thanks to software and hardware integration challenges. A "chimera," for the uninitiated, is described as a mythical creature whose anatomy comes from multiple animals, creating a hybrid of two or more creatures' best bits. It's also the name of the latest one-off creation from Koenigsegg, and it's certainly apt; the Koenigsegg Agera RS Chimera is an amalgam of technologies from the decade-old, record-breaking Agera RS, the fascinatingly innovative CC850, and the awe-inspiring Jesko - which just recently set four new acceleration records. There's also a hint of Regera in here, which had some impressive records of its own. As reported by Mr. JWW, the strictly one-off special edition was commissioned by FIA President Mohammed Ben Sulayem, and both he and one of Koenigsegg's engineers arrived at the same name. Let's take a closer look and see exactly why this is a hybrid, even though it's not electrified. Three Cars In One The Chimera was originally a regular Agera RS and one of several Koenigsegg megacars owned by Ben Sulayem, but he asked Christian and the team to initiate a special project on his behalf. Around the same time, the extraordinary Koenigsegg CC850 was revealed at Monterey Car Week 2022, introducing the innovative Engage Shift System (ESS). This was based on the already astonishingly fast nine-speed Light Speed Transmission, with new actuators and sensors added to enable the simulation of a manual transmission without a physical link between the shifter and the gearbox. Like the rest of the world, the FIA boss was enamored by this novel technology, and as a wealthy 'Egg collector, he asked for it to be put into his special Agera-based project. Christian pondered this and ultimately decided to fulfill the request, in the process turning Ben Sulayem's special edition into something of a development mule for the ESS. But unlike the CC850, the Chimera got the larger turbos of the Jesko, enabling around 1,280 horsepower on regular gas and up to 1,600 hp on E85. That means this is an Agera RS with a CC850 transmission and a Jesko engine. On paper, that sounds simple, but the reality was anything but... Three Shifting Experiences Took Three Years To Combine According to a video from YouTuber and Koenigsegg distributor Mr. JWW, this development process took three years and required the relocation of the battery, new mounts for the powertrain, new harnesses, new software and controllers, and even a new infotainment system. To ensure all the electronics worked seamlessly was a challenge, but then Ben Sulayem asked for another layer of intricacy, requesting that paddle shifters be added, like in the Jesko Absolut and Jesko Attack. In the CC850, you could only switch between the simulated manual mode and fully automatic shifts, but now, the Chimera's development has unlocked manually operable paddles, which have now been added as the only option you can add to a CC850. There was also significant relocation and redesigning of suspension components, with parts from the Jesko and the Regera forming the subframe and elements of the suspension, respectively. A new scoop for the new transmission's cooler was also added, but it looks like it was always planned. Christian von Koenigsegg says this is a true one-off, saying that it would be cheaper and easier to start something all-new from scratch than to mix new and old technologies again, and that it's simply "too much work" to tackle a retrofit project. The Chimera is not completed just yet, as there are still subtle elements to refine, such as the bite point of the clutch pedal, but these minor issues will surely be resolved soon. It's an amazing feat, combining three hypercars in one, and we can't even fathom how Koenigsegg will top this in the future, but we don't doubt that Christian and his team will continue to do just that.

Google Wallet can help you store your IDs, driving license, loyalty cards, concert tickets and more. You can also store your payment cards and use tap to pay to pay anywhere Google Pay is accepted. Google wallet is available in various countries but Google never launched it in India. Google let indian users stick with the Gpay which facilitates UPI payments. Tap to pay is not part of it. Also we can not store things such as IDs and Passes in indian version of Gpay. This might change and Google may launch Google Wallet in India. With the recent version of Google Wallet and Google Play Services, Google has added some flags and code which indicate that Google is working on something for Indian users regarding wallet. The first change I noticed recently when going through the Google Play Services apk was addition of two new flags Both flags are part of com.google.android.gms.pay package in the Google Play Services. This package contains all the flags for features of Gpay/Wallet. Google does server side flipping of flags to enable/disable features for users. So both these flags doesn't really provide any info about what features enabling these flags is going to bring. But the point here is that Google Wallet is not launched in India so why Google added these flags inside Play Services ? The answer could be that Google may be working on bringing Google Wallet to India. It can enable tap to pay, store payments and various other features for Indian users which we don't have in the current Gpay for India. I found similar flags in the analysis Google Wallet APK - These flags are also disabled by default. But this is again a clear indication of Google working towards something for Indian users. In both cases, enabling the flags doesn't bring anything noticeable UI or feature because there is nothing much added besides flags. Google has dogfood/testing versions internally, so the code will show up slowly in upcoming versions. The last piece of code I found is also from Google Play Services. In case you don't know, Google was working on Digilocker integration in the Google Files app which was supposed to bring your digital document inside the app such as driving license, COVID certificates, aadhar card. But Google has ditched the effort of bringing these features and they removed the "Important" tab (where digilocker was supposed to be integrated) from the Google Files app completely. So things are going to change and here is how. This is the code which I found in the Google Play Services - So the word "PASS" along with PAN, DRIVERS LICENCE, VACC CERTIFICATE & AADHAR CARD, is clear indication of the possibility of Google adding support for these directly through Google Wallet using Digilocker, just like Samsung Pass does it. This code is not old as I have checked older beta versions of Play Services where this code is not present. Here is a string which was added in a previous beta version a few weeks ago but I completely ignored it because it didn't make any sense without flags and the other code - This addition was surprising because there was nothing regarding digilocker before in the Play Services. In the words "pay_valuable", the "pay" to Wallet/Gpay and "valuable" refers to the things like Passes, loyalty cards and transit cards. Since we are talking about digilocker, these "valuable" are driving license, vaccination certificate, PAN card and Aadhar card which can be store in Google Wallet after digilocker integration. That's all about it. We will know more about it in upcoming app updates or maybe Google can itself annouce something about this.

July 9 (Reuters) - Futures linked to Canada's main stock index rose on the back of metal prices on Tuesday, while investors awaited U.S. Federal Reserve Chair Jerome Powell's congressional testimony on monetary policy later in the day. The S&P/TSX 60 futures were up 0.25% by 06:28 a.m. ET (1028 GMT). The Toronto Stock Exchange's materials sector was set to re Oil futures , dipped as fears over supply disruption eased after Hurricane Beryl, which hit major refineries along with the U.S. Gulf Coast, caused minimal impact. Markets will be heavily focussed on Powell's two-day monetary policy testimony before the Senate Banking Committee, starting at 10 a.m. ET (1400 GMT), which can help investors gauge the Fed's rate-cut path. Following last week's softer jobs data, market participants are now pricing in a 77% chance of a rate cut by the U.S. central bank in September. The main macro event for the markets this week will be the U.S. consumer prices data due on Thursday, which can help assess the trajectory of inflation in the world' biggest economy. Wall Street futures were also up on Tuesday after the S&P 500 (.SPX), opens new tab and Nasdaq (.IXIC), opens new tab touched record closing highs in the previous session. In Canada, fears of the economy slipping into recession advanced after the latest data showed that the unemployment rate rose to a 29-month high in June. Traders are now pricing in a 65% chance of another cut by the Bank of Canada, which already trimmed interest rates last month. In corporate news, Cenovus Energy (CVE.TO), opens new tab said it is demobilizing some staff at its Sunrise oil sands project in northern Alberta as a precaution due to the evolving wildfire situation in the area.

Incredible space photos like those from NASA don't look as stunning straight out of the telescope. They need significant processing, and a crucial part of that is sharpening. Coming to you from Unmesh Dinda with PiXimperfect, this fascinating video explores the APF-R plugin, developed by award-winning astrophotographer Christoph Kaltseis. APF-R stands for Absolute Point of Focus, and it's designed to enhance photo details without creating halos or artifacts. This technology has been used by space agencies with telescopes like the James Webb, and now, you can use it in Photoshop. The plugin allows for non-destructive editing, meaning you can adjust the radius and detail level without permanently altering your image. This feature is crucial for astrophotography, where preserving original details is vital. The video shows how APF-R compares to Photoshop's built-in sharpening tools. The plugin offers multiple rendering methods, each suited for different types of images. For instance, the "Center Weighted" method provides a balanced sharpening effect without making the image look overprocessed. Dinda explains how to fine-tune these settings to achieve the best results, making it clear why this plugin is a game-changer for photographers looking to enhance their images with precision. One notable feature of APF-R is its ability to work with different image types. The video demonstrates how the plugin enhances not just space photos but also landscapes and portraits. For portraits, APF-R can bring out skin textures and eye details without creating the unwanted halos that traditional sharpening methods often produce. Dinda also shows how to combine APF-R with other Photoshop tools, like Smart Sharpen, for even better results. This versatility makes APF-R a valuable addition to any photographer's toolkit. The plugin's cost is $50, which Dinda considers a bargain given its advanced capabilities. There's also a Creative Bundle subscription that includes APF-R and 20 other tools, offering great value for those looking to expand their editing options. Dinda provides discount codes in the video description, making this sophisticated tool more accessible. Check out the video above for the full rundown from Dinda.