A provocative new study reveals the complex effects of the space environment on human health, providing insight into potential damage to blood, cell structure and the immune system. The study focused on SpaceX's Inspiration4 mission, which successfully sent two men and two women into space in 2021 to orbit the Earth for three days and shed some light on the effects of space travel on the human body. The research data, derived directly from the Inspiration4 mission, shows that even a brief trip to space can significantly damage the human immune system, trigger an inflammatory response, and profoundly affect cell structure. In particular, space travel triggered unprecedented changes in cytokines that play a key role in immune response and muscle regulation but are not usually directly associated with inflammation. In particular, the study found a significant increase in muscle factors, which are physiological responses specific to skeletal muscle cells in microgravity, rather than a simple immune response. Although non-muscular tissues did not show changes in proteins associated with inflammation, specific leg muscles such as soleus and tibialis anterior muscles showed significant signs of metabolic activity, especially increased interleukin in the latter, further enhancing the activation of immune cells.

WASHINGTON, June 24 (Reuters) - Problems with Boeing's Starliner capsule, still docked at the International Space Station (ISS), have upended the original plans for its return of its two astronauts to Earth, as last-minute fixes and tests draw out a mission crucial to the future of Boeing's (BA.N), opens new tab space division. NASA has rescheduled the planned return three times, and now has no date set for it. Since its June 5 liftoff, the capsule has had five helium leaks, five maneuvering thrusters go dead and a propellant valve fail to close completely, prompting the crew in space and mission managers in Houston to spend more time than expected pursuing fixes mid-mission. Here is an explanation of potential paths forward for Starliner and its veteran NASA astronauts, Barry "Butch" Wilmore and Sunita "Suni" Williams. THE CURRENT SITUATION Starliner can stay docked at the ISS for up to 45 days, according to comments by NASA's commercial crew manager Steve Stich to reporters. But if absolutely necessary, such as if more problems arise that mission officials cannot fix in time, it could stay docked for up to 72 days, relying on various backup systems, according to a person familiar with flight planning. Internally at NASA, Starliner's latest targeted return date is July 6, according to this source, who spoke on condition of anonymity. Such a return date would mean that the mission, originally planned for eight days, instead would last a month. Starliner's expendable propulsion system is part of the craft's "service module." The current problems center on this system, which is needed to back the capsule away from the ISS and position it to dive through Earth's atmosphere. Many of Starliner's thrusters have overheated when fired, and the leaks of helium - used to pressurize the thrusters - appear to be connected to how frequently they are used, according to Stich.

A look at the day ahead in U.S. and global markets from Mike Dolan After an intense month focused on election risk around the world, markets quickly switched back to the more prosaic matter of the cost of money - and whether disinflation is resuming to the extent it allows borrowing costs to finally fall. Thursday's U.S. consumer price update for June is the key moment of the week for many investors - with the headline rate expected to have fallen two tenths of a percentage point to 3.1% but with 'core' rates still stuck at 3.4%. With Federal Reserve chair Jerome Powell starting his two-pronged semi-annual congressional testimony later on Tuesday, the consensus CPI forecast probably reflects what the central bank thinks of the situation right now - encouraging but not there yet. But as the U.S. unemployment rate is now back above 4.0% for the first time since late 2021, markets may look for a more nuanced approach from the Fed chair that sees it increasingly wary of a sudden weakening of the labor market as real time quarterly GDP estimates ebb again to about 1.5%. There were some other reasons for Fed optimism in the lead up to the testimony. The path U.S. inflation is expected to follow over coming years generally softened in June, amid retreating projections of price increases for a wide array of consumer goods and services, a New York Fed survey showed on Monday. Inflation a year from now was seen at 3% as of June - down from the expected rise of 3.2% in May - and five-year expectations fell to 2.8% from 3%. Crude oil prices are better behaved this week, too, falling more than 3% from the 10-week highs hit late last week and halving the annual oil price gain to 10%. The losses on Tuesday came after a hurricane that hit a key U.S. oil-producing hub in Texas caused less damage than many in markets had expected - easing concerns over supply disruption. Before Powell starts speaking later, there will also be an update on U.S. small business confidence for last month.

Incredible space photos like those from NASA don't look as stunning straight out of the telescope. They need significant processing, and a crucial part of that is sharpening. Coming to you from Unmesh Dinda with PiXimperfect, this fascinating video explores the APF-R plugin, developed by award-winning astrophotographer Christoph Kaltseis. APF-R stands for Absolute Point of Focus, and it's designed to enhance photo details without creating halos or artifacts. This technology has been used by space agencies with telescopes like the James Webb, and now, you can use it in Photoshop. The plugin allows for non-destructive editing, meaning you can adjust the radius and detail level without permanently altering your image. This feature is crucial for astrophotography, where preserving original details is vital. The video shows how APF-R compares to Photoshop's built-in sharpening tools. The plugin offers multiple rendering methods, each suited for different types of images. For instance, the "Center Weighted" method provides a balanced sharpening effect without making the image look overprocessed. Dinda explains how to fine-tune these settings to achieve the best results, making it clear why this plugin is a game-changer for photographers looking to enhance their images with precision. One notable feature of APF-R is its ability to work with different image types. The video demonstrates how the plugin enhances not just space photos but also landscapes and portraits. For portraits, APF-R can bring out skin textures and eye details without creating the unwanted halos that traditional sharpening methods often produce. Dinda also shows how to combine APF-R with other Photoshop tools, like Smart Sharpen, for even better results. This versatility makes APF-R a valuable addition to any photographer's toolkit. The plugin's cost is $50, which Dinda considers a bargain given its advanced capabilities. There's also a Creative Bundle subscription that includes APF-R and 20 other tools, offering great value for those looking to expand their editing options. Dinda provides discount codes in the video description, making this sophisticated tool more accessible. Check out the video above for the full rundown from Dinda.

SEOUL, July 9 (Reuters) - Samsung Electronics (005930.KS), opens new tab said on Tuesday it won an order from Japanese artificial intelligence company Preferred Networks to make chips for AI applications using the South Korean firm's 2-nanometre foundry process and advanced chip packaging service. It is the first order Samsung has revealed for its cutting-edge 2-nanometre chip contract manufacturing process. Samsung did not elaborate on the size of the order. The chips will be made using high-tech chip architecture known as gate all-around (GAA) and multiple chips will be integrated in one package to enhance inter-connection speed and reduce size, Samsung said in a statement. South Korea's Gaonchips Co (399720.KQ), opens new tab designed the chips, Samsung said. The chips will go toward Preferred Networks' high-performance computing hardware for generative AI technologies such as large language models, Junichiro Makino, Preferred Networks vice president and chief technology officer of computing architecture, said in the statement.