A provocative new study reveals the complex effects of the space environment on human health, providing insight into potential damage to blood, cell structure and the immune system. The study focused on SpaceX's Inspiration4 mission, which successfully sent two men and two women into space in 2021 to orbit the Earth for three days and shed some light on the effects of space travel on the human body. The research data, derived directly from the Inspiration4 mission, shows that even a brief trip to space can significantly damage the human immune system, trigger an inflammatory response, and profoundly affect cell structure. In particular, space travel triggered unprecedented changes in cytokines that play a key role in immune response and muscle regulation but are not usually directly associated with inflammation. In particular, the study found a significant increase in muscle factors, which are physiological responses specific to skeletal muscle cells in microgravity, rather than a simple immune response. Although non-muscular tissues did not show changes in proteins associated with inflammation, specific leg muscles such as soleus and tibialis anterior muscles showed significant signs of metabolic activity, especially increased interleukin in the latter, further enhancing the activation of immune cells.

A children's hospital in the Ukrainian capital was hit by a Russian missile on Monday as part of a wave of airstrikes across Ukraine that has killed at least 31 people and injured 154 others. "Russian terrorists have once again launched a massive missile attack on Ukrainian cities - Kiev, Dnipro, Kryvyi Rih, Slaviansk, Kramatorsk," said Ukrainian President Volodymyr Zelenskyy. Zelensky said Russia fired more than 40 missiles of different types at the five cities in daytime attacks, hitting residential buildings and public infrastructure. The Ukrainian air force said it intercepted 30 missiles. Authorities said the attack on Kiev killed seven people, while the attack on Kryvyi Rih, Zelensky's birthplace in central Ukraine, killed 10 and injured 47. United Nations Secretary-General António Guterres condemned the attacks, calling the assault on the Kiev hospital and another medical facility in the capital's Dniprovsky district "particularly egregious," said his spokesman, Stephane Dujarric. "Direct attacks on civilians and civilian objects are prohibited under international humanitarian law. Any such attacks are unacceptable and must cease immediately," Dujarric said. The U.N. Security Council will meet Tuesday to discuss the Russian strikes, diplomats said. The Russian Defense Ministry said the strikes targeted Ukrainian defense factories and a military aviation base and were successful. It denied striking any civilian facilities and claimed, without evidence, that photos from Kiev showed the damage was caused by a Ukrainian anti-aircraft missile. Ukrainian Air Force Colonel Yurii Ignat said Russia has been improving the effectiveness of its air strikes by equipping its missiles with enhanced features, including so-called heat decoys that can throw air defense systems off target. In comments sent to The Associated Press, he said the cruise missiles flew low in Monday's attack -- just 50 meters off the ground -- making them harder to hit. Western countries, led by the United States, have provided Ukraine with billions of dollars in arms support. They will hold a three-day NATO summit in Washington starting Tuesday to work out how to reassure Kiev of NATO's strong support and give Ukrainians hope that their country can survive the largest conflict in Europe since World War II. "Today's Russian missile strike that killed dozens of Ukrainian civilians and caused damage and loss of life to Kyiv's largest children's hospital is a horrifying reminder of Russia's brutality," U.S. President Joe Biden said in a statement Monday. "It is critical that the world continues to stand with Ukraine at this important moment and that we do not ignore Russian aggression." Biden said in the statement that he will meet with President Zelensky during the NATO summit in Washington this week "to make clear our unwavering support for Ukraine." Biden continued: "We will join our allies in announcing new measures to strengthen Ukraine's air defenses and help protect their cities and civilians from Russian attacks. The United States stands with the Ukrainian people." Czech President Petr Pavel said the hospital attack was "inexcusable" and he hoped the NATO summit would reach a consensus that Russia is "the greatest threat and we must be fully prepared to deal with it." Zelensky said during a visit to Poland that he hoped the NATO summit would provide Ukraine with more air defense systems. The Ukrainian leader said rescuers were digging through the rubble of the Ohmatdit Children's Hospital in Kyiv and that the number of casualties was not yet known. Kyiv Mayor Vitali Klitschko said at least 16 people were injured, including seven children, and the attack caused a two-story wing of the hospital to partially collapse. Doors and windows were blown off the hospital's 10-story main building, and the walls were charred. The floor of one room was splattered with blood. Hospital officials said the intensive care unit, operating room and oncology department were damaged.

New York CNN — A record number of passengers are expected to pass through US airports this holiday travel week. You’d think this would be a great time to run an airline. You’d be wrong. Airlines face numerous problems, including higher costs, such as fuel, wages and interest rates. And problems at Boeing mean airlines have too few planes to expand routes to support a record numbers of flyers. Strong bookings can’t entirely offset that financial squeeze. The good news for passengers is they will be spared most of the problems hurting airlines’ bottom lines — at least in the near term. Airfares are driven far more by supply and demand, not their costs. But in the long run, the airlines’ difficulties could mean fewer airline routes, less passenger choice and ultimately a less pleasant flying experience. Profit squeeze Industry analysts expect airlines to report a drop of about $2 billion in profit, or 33%, when they report financial results for the April to June period this year. That would follow losses of nearly $800 million across the industry in the first quarter. Labor costs and jet fuel prices, the airlines’ two largest costs, are both sharply higher this year. Airline pilot unions just landed double-digit pay hikes to make up for years of stagnant wages; flight attendant unions now want comparable raises. Jet fuel prices are climbing because of higher demand in the summer. According to the International Air Transport Association’s jet fuel monitor, prices are up 1.4% in just the last week, and about 4% in the last month. Adding to the airlines’ problems is the crisis at Boeing, as well as the less-well-publicized problems with some of the jet engines on planes from rival Airbus. Since an Alaska Airlines Boeing 737 Max jet lost a door plug on a January 5 flight, leaving a gaping hole in the side of the plane 10 minutes after takeoff, the Federal Aviation Administration has limited how many jets Boeing can make over concerns about quality and safety. As a result, airlines have dramatically reduced plans to expand their fleets and replace older planes with more fuel efficient models. In some cases, airlines have asked pilots to take time off without pay, and carriers such as Southwest and United have announced pilot hiring freezes. In addition to the problems at Boeing, hundreds of the Airbus A220 and A320 family of jets globally have also been grounded for at least a month or more to deal with engine problems. Just about all the planes with those engines have been out of sevice for at least a few days to undergo examinations. And Airbus has also cut back the number of planes it expects to deliver to airlines this year because of supply chain problems. Problems for flyers For now, competition in the industry remains fierce: There are 6% more seats available this month compared to July of 2023, according to aviation analytics firm Cirium. And that’s helped to drive fares down — good news for passengers, but more bad news for airlines’ profits. Southwest announced in April that it would stop serving four airports to trim costs — Bellingham International Airport in Washington state, Cozumel International Airport in Mexico, Syracuse Hancock International Airport in New York and Houston’s George Bush Intercontinental Airport. Many more cities lost air service during the financial hard times of the pandemic. While upstart airlines are driving prices lower for travelers, those discount carriers might not survive long term. As the major carriers are making less money, many of the upstarts are flat-out losing money.

July 8 (Reuters) - Microsoft (MSFT.O), opens new tab intends to offer Apple's (AAPL.O), opens new tab iOS-based devices to its employees in China to access authentication apps, a company spokesperson said on Monday, citing absence of Google's (GOOGL.O), opens new tab Android services in the country. Microsoft has been under increased scrutiny after a series of security breaches, the latest being that of Russian hackers who spied and accessed emails of the company's employees and customers earlier this year. The development was first reported by Bloomberg News, which, citing an internal memo, said the Windows OS-maker instructed its employees in China to use Apple devices at workplace from September. As a part of Microsoft's global Secure Future Initiative, the move to switch to iOS-devices stems from the lack of availability of Google Play Store in China that limits its employees' access to security apps such as Microsoft Authenticator and Identity Pass, the report added. "Due to the lack of availability of Google Mobile Services in this region, we look to offer employees a means of accessing these required apps, such as an iOS device," a company spokesperson told Reuters in an email. Microsoft is among those U.S. companies that have a strong presence in China. It entered the Chinese market in 1992 and also operates a large research and development center in the country. The company will provide iPhone 15 models to employees, currently using Android handsets across China, including Hong Kong, the Bloomberg report said.

CAIRO/GAZA, July 6 (Reuters) - At least 16 people were killed in an Israeli strike on a school sheltering displaced Palestinian families in central Gaza on Saturday, the Palestinian health ministry said, in an attack Israel said had targeted militants. The health ministry said the attack on the school in Al-Nuseirat killed at least 16 people and wounded more than 50. The Israeli military said it took precautions to minimize risk to civilians before it targeted the gunmen who were using the area as a hideout to plan and carry out attacks against soldiers. Hamas denied its fighters were there. At the scene, Ayman al-Atouneh said he saw children among the dead. "We came here running to see the targeted area, we saw bodies of children, in pieces, this is a playground, there was a trampoline here, there were swing-sets, and vendors," he said. Mahmoud Basal, spokesman of the Gaza Civil Emergency Service, said in a statement that the number of dead could rise because many of the wounded were in critical condition. The attack meant no place in the enclave was safe for families who leave their houses to seek shelters, he said. Al-Nuseirat, one of Gaza Strip's eight historic refugee camps, was the site of stepped-up Israeli bombardment on Saturday. An air strike earlier on a house in the camp killed at least 10 people and wounded many others, according to medics. In its daily update of people killed in the nearly nine-month-old war, the Gaza health ministry said Israeli military strikes across the enclave killed at least 29 Palestinians in the past 24 hours and wounded 100 others.