A provocative new study reveals the complex effects of the space environment on human health, providing insight into potential damage to blood, cell structure and the immune system. The study focused on SpaceX's Inspiration4 mission, which successfully sent two men and two women into space in 2021 to orbit the Earth for three days and shed some light on the effects of space travel on the human body. The research data, derived directly from the Inspiration4 mission, shows that even a brief trip to space can significantly damage the human immune system, trigger an inflammatory response, and profoundly affect cell structure. In particular, space travel triggered unprecedented changes in cytokines that play a key role in immune response and muscle regulation but are not usually directly associated with inflammation. In particular, the study found a significant increase in muscle factors, which are physiological responses specific to skeletal muscle cells in microgravity, rather than a simple immune response. Although non-muscular tissues did not show changes in proteins associated with inflammation, specific leg muscles such as soleus and tibialis anterior muscles showed significant signs of metabolic activity, especially increased interleukin in the latter, further enhancing the activation of immune cells.

McDonald's China, together with its four major suppliers announced the launch of an industrial park in Xiaogan city, Central China's Hubei Province on Wednesday, highlighting the importance of Chinese market in terms of supply chain for food business. With a combined investment of 1.5 billion yuan ($206 million), the park, named Hubei Smart Food Industrial Park, is a joint project with Bimbo QSR, XH Supply Chain, Tyson Foods Inc, and Zidan, according to information provided to the Global Times. The park is expected to produce 34,000 tons of meat products, 270 million buns, 30 million pastries, and 2 billion packaged products annually. It also features a 25,000-square-meter high-standard automated warehouse for frozen, refrigerated, and dry goods, reducing logistics time by 90 percent from manufacturing to arriving at the destination. Leveraging local geographical advantages, the park will become a supply hub for McDonald's in central and western China, enhancing supply efficiency and stability for its outlets there, the company said. "McDonald's has been deeply rooted in China for over 30 years, and the park is an echo of our long-term development in China," said Phyllis Cheung, CEO of McDonald's China. "Without any long-term strategy, we don't have any structural advantage in China," Cheung noted. The US food giant continues to expand its business map in China. As of the end of June in 2024, there were over 6,000 restaurants and over 200,000 employees in the market. China has become the second largest and fastest-growing market of McDonald's. In 2023, McDonald's China unveiled the ambition of operating 10,000 restaurants by 2028. To support this, McDonald's and its suppliers have invested over 12 billion yuan from between 2018 to 2023 to develop new production capacities and enhance supply chain sustainability. Observers said that the industrial park reflect foreign companies' confidence in operating in China as the country takes concrete measures in furthering reform and opening-up. China's foreign direct investment from January to May 2024 reached 412.51 billion yuan, with the number of newly-established foreign-backed companies reaching 21,764, rising by 17.4 percent year-on-year, data from China's Ministry of Commerce revealed. According to a recent survey by the American Chamber of Commerce in China, the majority of US companies saw improved profitability in China in 2023, and half of the survey participants put China as their first choice or within their top three investment destinations globally. Olaf Korzinovski, EVP of Volkswagen China, who is responsible for production and components, also shared his understanding of supply chains in China with the Global Times. Volkswagen has been operating in China for about 40 years. "In order to seize greater value for our customers," Volkswagen Group is stepping up pace of innovation in China, and systematically purshing forward the digitalization process, Korzinovski noted, adding the company is strengthening local capabilities with accelerated decision-making efficiency. Global Times

A look at the day ahead in U.S. and global markets from Mike Dolan After an intense month focused on election risk around the world, markets quickly switched back to the more prosaic matter of the cost of money - and whether disinflation is resuming to the extent it allows borrowing costs to finally fall. Thursday's U.S. consumer price update for June is the key moment of the week for many investors - with the headline rate expected to have fallen two tenths of a percentage point to 3.1% but with 'core' rates still stuck at 3.4%. With Federal Reserve chair Jerome Powell starting his two-pronged semi-annual congressional testimony later on Tuesday, the consensus CPI forecast probably reflects what the central bank thinks of the situation right now - encouraging but not there yet. But as the U.S. unemployment rate is now back above 4.0% for the first time since late 2021, markets may look for a more nuanced approach from the Fed chair that sees it increasingly wary of a sudden weakening of the labor market as real time quarterly GDP estimates ebb again to about 1.5%. There were some other reasons for Fed optimism in the lead up to the testimony. The path U.S. inflation is expected to follow over coming years generally softened in June, amid retreating projections of price increases for a wide array of consumer goods and services, a New York Fed survey showed on Monday. Inflation a year from now was seen at 3% as of June - down from the expected rise of 3.2% in May - and five-year expectations fell to 2.8% from 3%. Crude oil prices are better behaved this week, too, falling more than 3% from the 10-week highs hit late last week and halving the annual oil price gain to 10%. The losses on Tuesday came after a hurricane that hit a key U.S. oil-producing hub in Texas caused less damage than many in markets had expected - easing concerns over supply disruption. Before Powell starts speaking later, there will also be an update on U.S. small business confidence for last month.

At the beginning of this year, Elon Musk had a fortune of $251 billion and could almost single-handedly solve world hunger. However, Tesla's stagnant sales, the endless struggle to buy Twitter, and the volatility of Tesla's stock price meant he lost a lot of money this year. According to Forbes, Musk is the billionaire with the most losses so far this year, with his wealth shrinking at a rate of about $5 billion a month. According to the website, his wealth shrank by more than 10% from the end of 2023 to June 28, 2024. As the website explains: Between December 31, 2023, and June 28, the last day of regular stock market trading for the first half of the year, Musk's net worth fell from $251.3 billion to $221.4 billion, a bigger drop than any other billionaire tracked by Forbes, but Musk remains the richest person on the planet. The main reason for the dip in Musk's pocketbook is that a Delaware judge in January canceled Musk's then-record Tesla compensation package worth $51 billion, which led Forbes to cut the value of the equity award by 50 percent because of uncertainty about whether Musk would receive those stock options. Excluding that bonus, Musk's wealth has remained volatile over the past six months, with the value of his 13 percent stake in Tesla shrinking by about $20 billion as falling profits and car deliveries sent the stock down 20 percent. But that was partly offset by the growth of Musk's stake in his generative artificial intelligence startup xAI to $14.4 billion (Musk also has a roughly $75 billion stake in private aerospace company SpaceX, a $7 billion stake in social media company X, And smaller stakes in other companies, such as brain experimentation startup Neuralink).

More than 6,500 employees at South Korea's Samsung Electronics began a three-day mass strike on Monday (July 8), demanding an extra day of paid annual leave, higher pay raises and changes to the way performance bonuses are currently calculated. This is the largest organized strike in Samsung Electronics' more than half century of existence, and the union said that if this strike does not push employees' demands to be met, a new strike may be called. One of the core issues of the current dispute between the labor union and Samsung Electronics is raising wages and increasing the number of paid vacation days. The second demand is a pay rise. The union originally wanted a pay rise of more than 3% for its 855 employees, but last week they changed their demand to include all employees (rather than just 855). The third issue involves performance bonuses linked to Samsung's outsized profits - chip workers did not receive the bonuses last year when Samsung lost about Won15tn and, according to unions, fear they will still not get the money even if the company manages to turn around this year.