A provocative new study reveals the complex effects of the space environment on human health, providing insight into potential damage to blood, cell structure and the immune system. The study focused on SpaceX's Inspiration4 mission, which successfully sent two men and two women into space in 2021 to orbit the Earth for three days and shed some light on the effects of space travel on the human body. The research data, derived directly from the Inspiration4 mission, shows that even a brief trip to space can significantly damage the human immune system, trigger an inflammatory response, and profoundly affect cell structure. In particular, space travel triggered unprecedented changes in cytokines that play a key role in immune response and muscle regulation but are not usually directly associated with inflammation. In particular, the study found a significant increase in muscle factors, which are physiological responses specific to skeletal muscle cells in microgravity, rather than a simple immune response. Although non-muscular tissues did not show changes in proteins associated with inflammation, specific leg muscles such as soleus and tibialis anterior muscles showed significant signs of metabolic activity, especially increased interleukin in the latter, further enhancing the activation of immune cells.

On the 8th, the Argentine government promulgated the "Foundations and Starting Points for Argentine Freedom" comprehensive bill and a package of fiscal measures, marking the official entry into force of the government reform bill. According to the official gazette of the Argentine government, Argentine President Milley, Chief Cabinet Minister Guillermo Francos and Economy Minister Luis Caputo jointly signed Decrees No. 592 and No. 593 to promulgate these two new reform measures. The comprehensive bill declared Argentina to enter a one-year public emergency in the administrative, economic, financial and energy fields, and granted the president special powers in these fields. It also includes the relaxation of economic regulations, labor reforms and the implementation of a large-scale investment incentive system. The package of fiscal measures involves anti-money laundering, tax deferral, tariffs, re-imposition of high-salary income tax and reduction of personal property taxes. On June 28, after six months of negotiations, the two reform bills were finally passed by the Argentine Congress.

NEW DELHI, July 9 (Reuters) - India's beleaguered Paytm (PAYT.NS), opens new tab has secured approval from a government panel that oversees investments linked to China to invest 500 million rupees ($6 million) in a key subsidiary, three sources with direct knowledge of the matter said. The approval, which still has to be vetted by the finance ministry, will remove the main stumbling block to the unit, Paytm Payment Services, resuming normal business operations. Paytm Payment Services is one of the biggest remaining parts of the fintech firm's business, accounting for a quarter of consolidated revenue in the financial year ended March 2023. A separate unit, Paytm Payments Bank, was wound down this year by order of the central bank due to persistent compliance issues, triggering a meltdown in Paytm's stock. The government panel had earlier held back approval due to concerns about the 9.88% stake in Paytm held by China's Ant Group. India has intensified scrutiny of Chinese businesses since a 2020 border clash between the two countries. All in all, Paytm has been waiting for the nod from the government panel for about two years and without it, it would have had to also wind down its payment services business, which was forbidden from taking on new customers in March 2023. Once the approval has been formalised, it will be able to seek a so-called "payment aggregator" licence from the Reserve Bank of India. The sources, two of whom are government sources, declined to be identified as the decision has not been formally announced. India's foreign, home, finance and industries ministries, whose representatives sit on the panel, did not reply to emails seeking comment. A Paytm spokesperson said the company does not comment on market speculation. "We will continue to make disclosures in compliance with our obligations under the SEBI Regulations, and will inform the exchanges when there is any new material information to share," the spokesperson said.

Japan and the Philippines signed an important defense agreement, and the two sides became "quasi-allies". On July 8, local time, Japan and the Philippines signed the "Reciprocal Access Agreement" in Manila. The agreement will relax restrictions on the movement of personnel between the Japanese Self-Defense Forces and the Philippine military during joint exercises, mutual visits and other operations in each other's countries. In response, Chinese Foreign Ministry spokesman Lin Jian responded at a regular press conference on the 8th that exchanges and cooperation between countries should not undermine mutual understanding and trust between regional countries, should not undermine regional peace and stability, and should not target third parties or undermine the interests of third parties. The Asia-Pacific region does not need military groups, let alone "small circles" that provoke camp confrontation and instigate a "new Cold War". Any actions that undermine peace and stability in the region and undermine unity and cooperation in the region will arouse the vigilance and common opposition of the people in the region. Japan and the Philippines upgraded to a "quasi-alliance" relationship On the same day, a "2+2" meeting attended by the foreign ministers and defense ministers of Japan and the Philippines was held in Manila. Japanese Defense Minister Minoru Kihara and Foreign Minister Yoko Kamikawa attended the talks with Philippine Defense Minister Gilbert Teodoro and Foreign Minister Enrique Manalo. This is the second Japan-Philippines "2+2" meeting. The last one was held in Tokyo in April 2022. Witnessed by Philippine President Marcos, the two sides signed the "Reciprocal Access Agreement". Marcos expressed the hope that the bilateral relations between the Philippines and Japan and the trilateral cooperation between the Philippines, Japan and the United States will be further deepened. The "Reciprocal Access Agreement" is also known as the "Military Visits Agreement". Military and defense cooperation between sovereign states, especially sending troops into each other's territory, usually faces complicated procedures and other problems. In order to simplify the procedures, the two countries will reach relevant agreements to simplify the approval procedures for the entry of troops from both sides into each other's countries, and facilitate mutual visits and joint military activities between the two countries' troops. The "Reciprocal Access Agreement" was born. Take the "Reciprocal Access Agreement" signed by Japan and Australia (full name "Agreement between Japan and Australia on Promoting Mutual Access and Cooperation Facilitation between the Japanese Self-Defense Forces and the Australian Defense Force") as an example. The agreement has 29 articles, covering many areas such as entry and exit procedures for troops, jurisdiction, taxation, cost burden and compensation. The key is to simplify the entry and exit procedures for visiting troops and their members, ships, aircraft, etc., relax restrictions on the transportation of weapons, ammunition and materials carried by visiting troops, and provide a legal basis for the two countries' troops and weapons and equipment to enter each other's territory. Japan and the Philippines signed the "Reciprocal Access Agreement", making the Philippines the third country to conclude this agreement with Japan after Australia and the United Kingdom. Cai Liang, Secretary-General and Researcher of the China-Japan Relations Research Center of the Shanghai Institute for International Studies, analyzed to The Paper (www.thepaper.cn) that Japan and the Philippines have their own strategic considerations for signing the "Reciprocal Access Agreement". As for the Philippines, due to its limited strength, it does not exclude any foreign power willing to strengthen military cooperation with the Philippines from intervening in the South China Sea situation. Therefore, it can be seen that in the past two years, the Philippines has actively promoted Australia, France, India and other countries to intervene in the South China Sea and strengthen military cooperation with them, involving intelligence, weapons and equipment, and training and exercises. "Japan's purpose is very simple. Strengthening military cooperation with the Philippines is to strategically balance China. The United States and the Philippines are allies, and the US-Japan alliance has been upgraded to a 'quasi-alliance'. The military cooperation between the United States, Japan and the Philippines has been upgraded to a new level." Cai Liang said, "The signing of an important defense agreement between Japan and the Philippines will make it easier for Japan to intervene in the South China Sea situation and seek the 'three seas linkage' of the East China Sea, the South China Sea, and the Taiwan Strait, in order to better respond to China's strategy and enhance its international influence." As for whether the signing of the "Reciprocal Access Agreement" means that Japan will deploy the Self-Defense Forces in the Philippines, Cai Liang pointed out that this agreement only simplifies the procedures for the troops of both sides to enter each other's territory, and is more suitable for short-term training, military exercises, etc., and is not a long-term deployment of the Self-Defense Forces in the Philippines. The two countries deepen military cooperation The Philippine presidential office also said in a statement that Japan is one of the four major strategic partners of the Philippines, and the two countries have established a strategic partnership for more than ten years. It seems no coincidence that Japan and the Philippines signed the "Reciprocal Access Agreement" at this time. Recently, China-Philippines relations have become tense around the situation in the South China Sea. The Global Times quoted Japan's Kyodo News Agency as saying that the two sides are seeking to strengthen cooperation against China. Minoru Kihara said last week: "The Philippines is located in a strategically important region, occupies a key position on Japan's sea lanes, and is also an ally of the United States. Joint training and strengthening cooperation with the Philippines are of great significance to the realization of a 'free and open Indo-Pacific region'." Cai Liang said that Japan's intervention in the South China Sea situation is mainly to reduce strategic pressure in the East China Sea and southwest of Japan, but it is not conducive to peace and stability in the South China Sea. It is reported that Japan and the Philippines began negotiations on the agreement in November last year. The signing of the "Reciprocal Access Agreement" by the two sides lays the foundation for the two countries to strengthen bilateral and even multilateral military cooperation in the future. The Japanese government intends to allow the Self-Defense Forces to formally participate in the annual US-Philippines "Shoulder to Shoulder" joint exercises around the Philippines after the agreement comes into effect. The Self-Defense Forces previously participated in the "Shoulder to Shoulder" exercises as observers, and will be able to formally participate after signing the agreement. In April this year, the United States and the Philippines held the largest "Shoulder to Shoulder" exercise to date, involving 5,000 Philippine personnel and 11,000 US personnel. The military exercise also included about 150 Australian military personnel and 100 French naval personnel. According to the plan, 14 countries including Japan and India sent personnel as observers. The "Typhon" medium-range missile launch system deployed by the US military on Luzon Island in the Philippines for the first time participated in the exercise, which aroused great attention from all walks of life. In terms of weapons and equipment exports, Japan and the Philippines have gradually strengthened military cooperation in recent years. The Philippines recently agreed to purchase five Coast Guard patrol ships from Japan to enhance its patrol capabilities in the South China Sea. Defense News reported in November last year that the Philippines had received an early warning radar system from Japan in 2023, the first major equipment transfer since the Japanese government lifted the postwar defense export ban in 2014. The Japanese Ministry of Foreign Affairs stated that Kamikawa mentioned topics such as defense equipment transfer, "government security capability enhancement support" (OSA), and economic and trade cooperation. The OSA project was created by the Kishida government and plans to allocate billions of yen in budget to assist the military construction of the Philippines and other countries, including providing the Philippines with 5 sets of coastal surveillance radars. Regarding Japan's relaxation of restrictions on defense equipment exports, the Chinese Ministry of Defense previously responded that Japan has continuously broken through the constraints of the "peace constitution" and the principle of "exclusive defense", and has been making small moves in the field of military security, which has aroused high vigilance and strong concern from the international community. China requires Japan to deeply reflect on its history of aggression, attach importance to the security concerns of its Asian neighbors, adhere to the path of peaceful development, and win the trust of its Asian neighbors and the international community with practical actions.

White House spokeswoman Karina Jean-Pierre denied a report in the U.S. media on the 8th that President Joseph Biden did not receive treatment for Parkinson's disease. Biden had the first televised debate of the 2024 presidential election with Republican opponent Donald Trump on June 27, and his poor performance on the spot triggered discussions about his physical condition. The New York Times reported that a doctor specializing in the treatment of Parkinson's disease had "visited" the White House eight times from August last year to March this year. Facing the media's questions about Biden's health, Jean-Pierre asked and answered himself at a regular White House press conference on the 8th: "Has the president received treatment for Parkinson's disease? No. Is he currently receiving treatment for Parkinson's disease? No, he is not. Is he taking medication for Parkinson's disease? No." Jean-Pierre said Biden had seen a neurologist three times, all related to his annual physical examination. She also took out the report issued by the doctor after Biden's most recent physical examination in February this year. The report said, "An extremely detailed neurological examination was once again reassuring" because no symptoms consistent with stroke, multiple sclerosis or Parkinson's disease were found. The doctor who went to the White House mentioned by the New York Times is Kevin Kanal, a neurology and movement disorder expert at the Walter Reed National Military Medical Center in Maryland and an authority on Parkinson's disease. Jean-Pierre suggested that the doctor might have come to treat military personnel on duty at the White House.